ncRNA name | rno-miR-29b |
ncRNA Category | miRNA |
Disease name | diabetic retinopathy (DR) |
Species | Rattus norvegicus |
Tissues/Cell_line | rat retinal Müller cells; rat retinal Müller cell line rMC-1 |
Methods | qPCR, Western blot, high-performance liquid chromatography (HPLC), transfection, luciferase reporter assay |
Expression pattern | down-regulated |
Functional description | Downregulation of microRNA 29a/b, mediated by the sonic hedgehog-glioma-associated oncogene homolog 1 signalling pathway, exacerbated diabetic retinopathy by upregulating Forkhead box protein O4. |
PubMed ID | 29409329 |
Year | 2018 |
Title | Downregulation of MicroRNA 29a/b exacerbated diabetic retinopathy by impairing the function of Müller cells via Forkhead box protein O4. |
Drug-related ncRNA | NO |
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